Diflunisal therapy for cardiac ATTR amyloidosis: a longitudinal, prospective, single centre study
نویسندگان
چکیده
Background The transthyretin (TTR) stabilizer diflunisal has been shown to reduce the rate of progression of neurological manifestations in patients with hereditary ATTR amyloidosis. However, data on the effect of diflunisal on cardiac structure and function in amyloidotic hearts are lacking. We report the echocardiographic profiles and cardiac biomarkers of patients with either mutant (M) or wild-type (WT) TTR-related cardiac amyloidosis (ATTR-CA) who received treatment with diflunisal compared to matched untreated patients.
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2015